Pós-Graduação em Biologia de Sistemas

+55 11 3091-7258

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Profa. Dra. Claudimara Ferini Pacicco Lotfi

 

 

Research Interests

Study of the action of hormones and peptides in normal and tumor adrenocortical.

Description

The group studies the action of hormones and growth factors in signaling pathways and the expression of genes involved in the proliferation and death of adrenal cortex cells. They used cell lines, adrenal primary cultures of rat and human, and tumor cell cultures derived from patient tumor for drug testing and molecular markers in carcinomas. They also used in vivo models such rats treated with dexamethasone and mice Pomc-knockout inducible for the study of ACTH and synthetic N-terminal-Pomc peptides.