Investigating the neuroanatomical aspects of the pathophysiology of pain in behavioral models.
The goal of the research is to investigate the neuroanatomical aspects of the pathophysiology of pain in different behavioral models. Further, to evaluate the possible role of non-pharmacological therapies as a way of improving the conventional treatment. These processes are studied in different models of nociception as neuropathic and muscle pain, using different techniques such as immunohistochemistry, immunoblotting, and therapies with low laser therapy and neural mobilization. The goal is to observe possible changes of glial cells, cytokines, nitric oxide and different inflammatory mediators, correlating with nociceptive behavioral models after acute injury and / or chronic injury. Physical therapy has shown, by the Neural Mobilization and Laser Therapy technique, an improvement in the quality of life of patients with different types of pain. The group’s aim is to use the neural mobilization technique and laser therapy, already standardized and published by the laboratory, in experimental animals and / or patients, since both techniques are able to induce a behavioral improvement in patients with chronic and muscle pain.